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Animal Cell and its structure Simulation Playbook

Before Starting the Simulation:
  • Ensure all VR headsets are charged and properly calibrated
  • Review safety guidelines for VR equipment use
  • Show students the essential VR gestures and controls
  • Plan your time: allocate 20 minutes for interaction and 10–15 minutes for reflection
During the Simulation:
  • Designate student helpers to assist their peers
  • Circulate throughout the classroom to support struggling students
  • Guide students to observe and document cellular changes
  • Prompt students to share their observations verbally
Group Organization:
  • For classes with limited devices, form triads: one in VR, two observing/discussing
  • Rotate roles every 5–7 minutes
  • Provide printed diagrams of cellular structures for note-taking during observation
Troubleshooting Technical Issues:
  • Preload simulation and test each headset prior to class
  • Keep a backup tablet with 2D version of the lab in case of headset malfunction
  • Maintain clear VR boundaries and warn students about physical obstacles
Recommendations for Teachers

Before simulation:

  • Ask: “What do you think a cell needs to function?”
  • Show images of plant, fungal, and animal cells for comparison.

During simulation:

  • Pause after each action and ask students:
    “What did this organelle do?”
    “What changed?”

After simulation:

  • Have students complete a Venn diagram: plant vs animal vs fungal
  • Group task: write a story from the POV of a centrosome
1. Simulation Overview

Simulation title: Animal Cell VR Simulation

Description: The student enters an animal cell to restore its function by interacting with damaged organelles. They explore the internal environment and witness how each organelle contributes to cell life.

Simulation type: VR

Subject and age: Biology, Grades 6–8

Key topics:

  • Animal cell structure
  • Organelle functions
  • Differences between cells
  • Cell cycle and energy flow
2. Key Simulation Milestones
Time Simulation stage What happens before the action? What should be done? What happens after the action?
00:00 Enter simulation The student sees a laboratory with a table. On the table is a microscope and a model of a lancet as a sample. The student needs to press the trigger on the microscope. The student moves inside an animal cell.
00:31 Overview of organelles and instruction The student sees the entire cell with all its organelles. An instruction panel appears with guidance for the tasks ahead. The student needs to click on the cross to close the information panel. The panel closes and the student can begin working inside the cell.
00:52 Membrane One of the membrane channels is clogged with waste — four red hemispheres block the passage. The student must press the trigger on the red spheres to clear the membrane channel. After cleansing the channels, the four spheres disappear.
01:23 Nucleus Chromatin temporarily disappears, and the nucleolus turns red. The student needs to press the trigger on the nuclear envelope. Chromatin returns and the nucleolus returns to its lilac color.
01:57 Centriole (Centrosome) One of the centrioles in the centrosome pair is missing. The student needs to press the trigger at the centriole location. The missing centriole reappears in the centrosome.
02:40 Mitochondria One of the mitochondria has a faded, gray inner membrane. The student needs to press the trigger on the damaged mitochondrion. The mitochondrion returns to its original dark brown color.
03:13 Rough ER Ribosomes are missing from the rough ER, making it look like smooth ER. The student needs to press the trigger on the rough ER. Ribosomes reappear on the surface of the rough ER.
03:51 Golgi apparatus The Golgi animation has stopped. Yellow balls (packaged proteins and lysosomes) are no longer produced. The student needs to press the trigger on the Golgi apparatus. Animation resumes and yellow particles fly out, representing packaged proteins.
04:31 Lysosome One of the lysosomes has turned red. The student needs to press the trigger on the damaged lysosome. The lysosome returns to its original color.
05:12 Completion and exit The student returns to the laboratory starting area. No additional actions are required. The student is informed that the lab is complete.
3. Theoretical Anchors (from the scene)
  • Membrane (cell membrane) — a thin semi-permeable shell surrounding the cell and separating its internal contents from the external environment. It controls the movement of substances in and out of the cell, provides protection, and participates in cellular communication and signal transmission.
  • Nucleus — the control center of the cell that transmits DNA instructions for protein synthesis and cellular activities. It contains chromosomes made of DNA and proteins, regulates gene expression, and ensures that genetic information is properly maintained and passed to daughter cells during cell division.
  • Cytoplasm — the gel-like substance inside the cell that surrounds all organelles, providing the essential environment for biochemical processes and reactions. It contains water, proteins, carbohydrates, and other molecules needed for metabolism and supports transport through cytoplasmic streaming.
  • Mitochondria — the powerhouse organelles responsible for cellular respiration and ATP synthesis. They supply energy for all vital processes and are present in both plant and animal cells.
  • Endoplasmic Reticulum (ER) — a system of interconnected membrane channels involved in the synthesis, folding, modification, and transport of proteins and lipids. Includes rough ER (with ribosomes) and smooth ER (without ribosomes).
  • Golgi apparatus — a complex of flattened membrane sacs that receives, modifies, sorts, and packages proteins and lipids from the ER for delivery to their final destinations inside or outside the cell.
  • Lysosomes — membrane-bound organelles containing digestive enzymes used to break down waste materials, damaged organelles, and foreign particles through autophagy and heterophagy.
  • Centrosome (Centrioles) — a pair of perpendicular centrioles that organize the microtubule network essential for cell division. They form the spindle fibers that move chromosomes during mitosis.
4. Reflection Questions
  • What was the most critical organelle to repair and why?
  • How did the cell “come alive” as you restored each part?
  • What role do centrioles play during cell division?
  • Which organelle reminded you of a logistics center?
  • How does an animal cell differ from a plant or fungal cell?
5. Hard Skill Questions
  • What organelles are missing in animal cells compared to plant cells?
  • How do mitochondria produce energy, and why is it important?
  • Describe the role of the rough ER and how it interacts with the Golgi.
  • What is the function of lysosomes in waste processing?
  • Explain the structure and role of the centrosome.
6. Attachments
  • Video walkthrough
  • QR code to simulation
  • Organelle card sort
  • Assessment worksheet
  • Reflection journal prompt
  • Google Form quiz